The main objective of this study was to investigate modernism and relative deprivation in girls` tendency in the use of cosmetics. Today, among the range of young girls we have seen excessive use of cosmetics and this requirement could make industry to become more sustainable. Existing theoretical literature and previous research claim to influence modern appliances as a social pattern that has affected young people. This study was conducted to survey data collected through questionnaires. The population was all female students in Islamic Azad University of Tehran Medical Branch. The population was 800 subjects and 400 of them were selected randomly. The results indicate that there is a significant relationship between the relative deprivation of the use of cosmetics(r= 0/375) and the modernism with the use of cosmetics(r=0/53. There is a meaningful relationship between the modernists and the girls tend to use the cosmetics too. Structural equation modeling results indicated that RMSEA index was 0/058 proportion of Chi-square to the degrees of freedom (CMIN/DF) was 2/31, CFI was 0/90 and PCFI index was 0/82.Also the PNFI index in this study was 0/67 that indicated the value was acceptable.